Additive antianginal effect of verapamil in patients receiving propranolol.
نویسندگان
چکیده
منابع مشابه
The additive antianginal action of oral nifedipine in patients receiving propranolol: magnitude and duration of effect.
Ten men with stable angina not completely relieved by full doses of propranolol (mean 218 mg/day) were administered an oral dose of 10 mg of nifedipine or placebo on alternate mornings in a double-blind fashion. Patients had been trained in a protocol that precipitated angina after 3-6 minutes of bicycle exercise. On test days, with propranolol continued, bicycle exercise to angina or fatigue w...
متن کاملComparison of antianginal actions of verapamil and propranolol
Verapamil is a slow calcium channel blocker that has been in clinical use for almost 20 years as an antiarrhythmic agent. It also has an antianginal action,' but inconsistent results have been obtained in clinical trials owing to insufficient dosage.2 We found that the drug produced a significant decrease in the number of anginal attacks and the consumption of glyceryl trinitrate with improveme...
متن کاملComparison of the antianginal effectiveness of nifedipine, verapamil, and isosorbide dinitrate in patients receiving propranolol: a double-blind study.
Ten men with stable angina not fully relieved by optimal doses of propranolol were given on each of four mornings a single dose of 10 mg nifedipine, 120 mg verapamil, isosorbide dinitrate (5 to 30 mg, previously titrated to lower systolic blood pressure by 15 to 20 mm Hg), or placebo, in double-blind fashion. Bicycle exercise to angina was performed hourly for 8 hr thereafter. All three vasodil...
متن کاملComparison of antianginal actions of verapamil and propranolol.
Comparison of antianginal actions of verapamil and propranolol Verapamil is a slow calcium channel blocker that has been in clinical use for almost 20 years as an antiarrhythmic agent. It also has an antianginal action,' but inconsistent results have been obtained in clinical trials owing to insufficient dosage.2 We found that the drug produced a significant decrease in the number of anginal at...
متن کاملTHERAPY AND PREVENTION CORONARY ARTERY DISEASE Comparison of the antianginal effectiveness of nifedipine, verapamil, and isosorbide dinitrate in patients receiving propranolol: a double-blind study
Ten men with stable angina not fully relieved by optimal doses of propranolol were given on each of four mornings a single dose of 10 mg nifedipine, 120 mg verapamil, isosorbide dinitrate (5 to 30 mg, previously titrated to lower systolic blood pressure by 15 to 20 mm Hg), or placebo, in double-blind fashion. Bicycle exercise to angina was performed hourly for 8 hr thereafter. All three vasodil...
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ژورنال
عنوان ژورنال: BMJ
سال: 1982
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.284.6327.1472